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Gender‐related differences in visceral perception in health and irritable bowel syndrome
Author(s) -
KIM HYUN SEO,
RHEE POONGLYUL,
PARK JUNGHO,
LEE JUN HAENG,
KIM YOUNGHO,
KIM JAE JUN,
RHEE JONG CHUL
Publication year - 2006
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.2005.04060.x
Subject(s) - irritable bowel syndrome , medicine , perception , gastroenterology , biology , neuroscience
Background: Irritable bowel syndrome (IBS) is more common in female subjects, and IBS patients generally exhibit reduced pain thresholds to rectal distension. The aim of the present paper was to determine gender‐related differences in rectal perception in both healthy controls and IBS patients. Methods: Fifty‐nine IBS patients (age 20–65 years; mean, 39.2 years; 31 women, 28 men) with symptoms that fulfilled Rome‐II criteria and 21 healthy controls (age 25–58 years; mean, 37.8 years; 11 women, 10 men) were recruited. Participants completed a questionnaire regarding bowel symptoms and psychological distress, and maximal tolerable pressures were evaluated via barostat tests. Results: Although healthy women appear to have lower perception thresholds than men, significant gender differences in pain sensitivity were not detected ( P > 0.05). In addition, female patients with IBS also exhibited no enhanced colorectal perception, as compared with male IBS patients ( P > 0.05). Conclusions: No gender differences in visceral perception were determined to exist between the healthy controls and the IBS patients. Therefore, the increased prevalence of IBS in women may be related to another set of pathophysiological factors, and not to gender‐related differences in visceroperception.