Premium
Colour Doppler‐guided spectral analysis of gall‐bladder wall flow
Author(s) -
HAYAKAWA SHINYA,
GOTO HIDEMI,
HIROOKA YOSHIKI,
ITOH AKIHIRO,
TAKI TOMOYUKI,
WATANABE YOSHIHIRO,
HAYAKAWA TETSUO,
NAITOH YASUO
Publication year - 1998
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.1998.tb00635.x
Subject(s) - medicine , gall , adenomyomatosis , cholecystitis , gallbladder , bladder cancer , chronic cholecystitis , asymptomatic , blood flow , radiology , cancer , botany , biology
For the purpose of the present study to diagnose gall‐bladder cancers, which cannot be detected or are only partly visible by conventional ultrasonography (US), we attempted differential diagnoses of 69 patients with gall‐bladder diseases (12 with gall‐bladder cancer, five with acute cholecystitis, 11 with chronic cholecystitis, 27 with cholesterol polyp and 14 with adenomyomatosis) using the evaluation of gall‐bladder wall blood flow (GWBF). GWBF was evaluated by colour Doppler‐guided spectral analysis (CDSA). Thirty‐three healthy volunteers were selected as controls at random. Two parameters of GWBF, namely flow velocity and resistive index (RI), were compared between patients with gall‐bladder diseases and healthy volunteers. GWBF could be ultrasonically evaluated in 92 (90%) of 102 subjects. All 12 patients with gall‐bladder cancer had a significantly rapid blood flow value compared with other patients and healthy volunteers. There was no significant difference in RI among patients and healthy volunteers. When cut‐off level of the flow velocity was set at 30 cm/s, gall‐bladder cancer could be diagnosed by flow velocity with 100% sensitivity (12/12) and 96% specificity (50/52). Using the same cut‐off level of the flow velocity, 17 patients were analysed prospectively. In four asymptomatic gall‐bladder cancers and two acute cholecystitis cases with some symptoms, the flow velocity was over 30 cm/s. In two of four patients with gall‐bladder cancer, only a part of the tumour was visualized on conventional abdominal US. In conclusion, CDSA was more useful for diagnosing gall‐bladder lesions than the conventional abdominal US due to estimation of arterial flow velocity in the gall‐bladder wall.