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AETIOPATHOGENESIS OF HEPATOCELLULAR CARCINOMA
Author(s) -
TOYODA HIDENORI,
FUKUDA YOSHIHIDE,
KOYAMA YASUO,
NISHIMURA DAISAKU,
HOSHINO HIROSHI,
KATADA NAOYUKI,
KATO KATSUMOTO,
HAYAKAWA ETSUO
Publication year - 1996
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.1996.tb01854.x
Subject(s) - medicine , hepatocellular carcinoma , lymph node , lymph , biopsy , hepatectomy , lymphoma , lymph node biopsy , metastatic carcinoma , radiology , supraclavicular lymph nodes , carcinoma , pathology , surgery , resection , metastasis , cancer
Extrahepatic lymph node metastases from hepatocellular carcinoma (HCC) are usually observed in patients with advanced and poorly differentiated HCC. We encountered a patient with multiple, systemic lymph node metastases from a small HCC (18 mm in diameter), which was nodular and had a capsule at the time of resection (a partial hepatectomy of the postero‐inferior subsegment of the right lobe of the liver). Widespread lymphadenopathy resembling malignant lymphoma developed 2 months after surgery. A biopsy specimen from a supraclavicular lymph node revealed metastatic HCC. The patient died 2.5 months after the detection of the lymphadenopathy. Lymph node metastases can occur in small HCC less than 2 cm in diameter and may adversely affect the long‐term prognosis of patients with these curatively resectable small HCC.