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Lubrication of visceral movement and gastric motility by peritoneal surfactant
Author(s) -
HILLS BA
Publication year - 1996
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.1996.tb00083.x
Subject(s) - lubrication , pulmonary surfactant , medicine , boundary lubrication , stomach , phospholipid , peritoneal cavity , ex vivo , lamellar granule , motility , in vivo , pathology , anatomy , lung , materials science , composite material , membrane , biochemistry , microbiology and biotechnology , biology
Four studies are described as a means of evaluating the hypothesis that surface‐active phospholipid (SAPL) enhances the lubrication of gastric motility and visceral movement in general. In the first two studies, a lipid extract from ovine peritoneal rinsings was found to have remarkable antiwear capabilities ex vivo and to reduce friction to a remarkably low level as quantified by a coefficient of kinetic friction of 0.008 ± 0.002 ( n = 10). Moreover, this lipid extract demonstrated both these features of lubrication at high load. In other studies, peritoneal lipid extract was found to be highly surfaceactive, while many lamellar bodies (LB) have been identified in omentum and, by analogy with the lung and the stomach, would therefore appear to be a source of SAPL. Lubrication by peritoneal surfactant is discussed as another example of a ubiquitous barrier to abrasion and other potential insults common to all visceral surfaces.