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Serum α 2 ‐macroglobulin–trypsin complex and early recognition of severe acute pancreatitis after endoscopic retrograde pancreatography
Author(s) -
NAKAE YASUYUKI,
HAYAKAWA TETSUO,
KONDO TAKAHARU,
SHIBATA TOKIMUNE,
KITAGAWA MOTOJI,
SAKAI YUZO,
SOBAJIMA HIROSHI,
ISHIGURO HIROSHI,
TANIKAWA MAKOTO
Publication year - 1994
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.1994.tb01723.x
Subject(s) - medicine , acute pancreatitis , pancreatitis , gastroenterology , trypsin , abdominal pain , pancreatic disease , macroglobulin , pancreas , enzyme , biochemistry , chemistry
Serum α 2 ‐macroglobulin‐trypsin complex (α 2 M‐T) was measured to differentiate the elevation of serum pancreatic enzymes caused by severe acute pancreatitis from simple elevation after endoscopic retrograde pancreatography (ERP). A patient with severe acute pancreatitis demonstrated marked elevation of serum α 2 M‐T. In patients without severe acute pancreatitis, serum αM‐T did not rise in spite of elevated serum pancreatic enzymes. In conclusion, abdominal pain with elevated serum α 2 M‐T can be an early diagnostic clue to severe acute pancreatitis after ERP.