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Gastric mucosal barrier: Intergranular matrix of gastric surfactant in the mucous lining
Author(s) -
HILLS B. A.
Publication year - 1992
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.1992.tb00986.x
Subject(s) - medicine , pulmonary surfactant , matrix (chemical analysis) , gastric mucosa , gastroenterology , pathology , stomach , composite material , chemical engineering , materials science , engineering
Transmission electron microscopy of rat gastric mucosa fixed by a novel procedure designed for barriers to watersoluble solutes has shown that the intergranular matrix material of gastric mucus is oligolamellar surface‐active phospholipid. It is a gastric surfactant similar to that seen on deeper mucus‐free surfaces also exposed to acid.