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Significance of blood flow in the inferior and superior mesenteric veins for the formation of oesophageal varices
Author(s) -
SHIOMI SUSUMU,
KUROKI TETSUO,
UEDA TADASHI,
IKEOKA NAOKO,
NISHIGUCHI SHUHEI,
NAKAJIMA SHINYA,
KOBAYASHI KENZO,
MONNA TAKEYUKI,
OCHI HIRONOBU
Publication year - 1991
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.1991.tb01456.x
Subject(s) - medicine , inferior mesenteric vein , mesenteric vein , superior mesenteric vein , varices , blood flow , splenic vein , cirrhosis , portal hypertension , radiology , right gastric vein , portal venous pressure , portal vein
The degree of involvement of blood flow in the superior mesenteric vein and inferior mesenteric vein in the formation of oesophageal varices is not known. We have developed a method by which the contributions of these veins to portal blood flow can be evaluated simultaneously in a relatively non‐invasive way. An enteric‐coated capsule containing [ 123 I]iodoamphetamine (IMP) is given by mouth and 3 h later [ 123 I]IMP is instilled into the rectum. The data obtained are treated by computer to calculate the portal shunt index via the inferior and superior mesenteric veins. In chronic hepatitis and cirrhosis, when varices were absent, the difference in these indices was not significant. In the presence of varices, the portal shunt index via the inferior mesenteric vein was significantly higher than that via the superior mesenteric vein. It was suggested that the contribution of blood flow in the inferior mesenteric vein the portal/splenic axis is important in the formation of varices.