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Case‐control study on oesophageal cancer in southern Thailand
Author(s) -
CHONGSUVIVATWONG VIRASAKDI
Publication year - 1990
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.1990.tb01415.x
Subject(s) - medicine , confidence interval , logistic regression , alcohol consumption , relative risk , risk factor , case control study , cigarette smoking , cancer , odds ratio , environmental health , demography , surgery , alcohol , biochemistry , chemistry , sociology
A case‐control study was conducted in southern Thailand to test the hypothesis that alcohol consumption, smoking, rubber processing and nutritional deficiency were risk factors for oesophageal cancer. Cases ( n = 40) were recruited from patients admitted to the University Hospital, where the first interview took place. Age‐ and sex‐matched controls ( n = 129) were selected from closest neighbours of the case. The case: control ratio varied from 1:1 to 1:6, depending on the availability of controls. Logistic regression analysis gave a relative risk for drinking and smoking of 5.7 (95% confidence interval (CI) = 2.1–15.1), whereas the relative risk for alcohol drinking only was 4.7 (95% CI = 0.5–42) and for smoking only was 1.6 (95% CI = 0.7–4). Data on dietary habits were not analysed because of great variation. Rubber processing was not a significant risk factor. It was concluded that combined alcohol and cigarette consumption are important risk factors for oesophageal cancer in southern Thailand.