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Intra‐operative secretin test for the rapid evaluation of curative operation in a case of Zollinger‐Ellison syndrome
Author(s) -
AZUMA TAKESHI,
IMAMURA MASAYUKI,
SHIMADA YUTAKA,
INOKUCHI HIDETO,
KAWA KEIICHI
Publication year - 1988
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.1988.tb00225.x
Subject(s) - medicine , zollinger ellison syndrome , secretin , duodenum , pancreas , pancreatic head , gastrin , gastrinoma , surgery , gastroenterology , general surgery , secretion
The intra‐operative measurements of serum gastrin levels and an intra‐operative secretin test were carried out as the rapid evaluation of curative operation in a case of Zollinger‐Ellison syndrome (ZES). In this case, pre‐operative investigations suggested that the tumours were located in the head of the pancreas and the duodenal wall. The surgeon planned a pan‐creato‐duodenectomy. Serum gastrin levels were reduced after the resection of the head of the pancreas and duodenum, and the secretin test after resection was negative. The surgeon ensured that gastrinomas were resected completely during the operation. The secretin test carried out 1 month post operatively was also negative. The patient has experienced no further complications, to date. This case suggests that intra‐operative secretin test is useful for the rapid evaluation of curative operation in case of ZES.