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Use of viral vectors for vaccine production in plants
Author(s) -
Cañizares M Carmen,
Nicholson Liz,
Lomonossoff George P
Publication year - 2005
Publication title -
immunology and cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0818-9641
DOI - 10.1111/j.1440-1711.2005.01339.x
Subject(s) - biology , virology , plant virus , epitope , computational biology , production (economics) , viral infection , virus , computer science , antigen , genetics , macroeconomics , economics
The small size of plant viral genomes, the ease with which they can be manipulated, and the simplicity of the infection process is making the viral vectors an attractive alternative to the transgenic systems for the expression of foreign proteins in plants. One use of these virus expression systems is for vaccine production. There are two basic types of viral system that have been developed for the production of immunogenic peptides and proteins in plants: epitope presentation and polypeptide expression systems. In this review, we discuss advances made in this field.