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Relationships between Presence of the Eye Cup and Maintenance of Lens‐Forming Capacity in Larval Xenopus laevis
Author(s) -
Bosco Luigi,
Filoni Sergio
Publication year - 1992
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1992.tb00030.x
Subject(s) - xenopus , lens (geology) , cornea , enucleation , epidermis (zoology) , anatomy , vitreous chamber , biology , retina , ophthalmology , medicine , neuroscience , visual acuity , refractive error , paleontology , biochemistry , genetics , gene
The lentectomized eye of larval Xenopus laevis can regenerate a lens by a process of lens‐transdifferentiation of the cornea and pericorneal epidermis. These tissues can form the lens only when they become in direct communication with the environment of the vitreous chamber (neural retina) indicating that the eye cup plays a fundamental role in this process. In this work the role of the eye cup in the maintainance of the lens‐forming capacity of the cornea and pericorneal epidermis was studied by allowing these tissues to cover the enucleated orbit for different periods, and then implanting them into the vitreous chamber of the contralateral eye. Under these experimental conditions the maintainance of the lens‐forming capacity of the cornea and pericorneal epidermis showed no significant correlation with the time from enucleation to implantation.