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Maitotoxin, A Presumed Calcium Channel Activator, Induces the Acrosome Reaction in Mussel Spermatozoa
Author(s) -
NISHIYAMA ICHIRO,
MATSUI TAEI,
YASUMOTO TAKESHI,
OSHIO SHIGERU,
HOSHI MOTONORI
Publication year - 1986
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1986.00443.x
Subject(s) - acrosome reaction , asterias , mytilus , starfish , verapamil , activator (genetics) , calcium channel , calcium , chemistry , voltage dependent calcium channel , biology , biochemistry , fishery , ecology , organic chemistry , gene , in vitro
Maitotoxin, a presumed activator of the voltage‐sensitive calcium channel, induced the acrosome reaction in the mussel, Mytilus edulis at physiological pH and in the starfish, Asterias amurensis at pH 9.5. The induction of acrosome reaction by maitotoxin depended upon external Ca 2+ and was inhibited by two types of calcium channel blockers; verapamil and diltiazem. These results suggest that the activation of the voltage‐sensitive calcium channel takes an important part in the initiation of acrosome reaction in Mytilus and other animals.