Premium
Implications of Differential Chemotaxis and Cohesiveness for Cell Sorting in the Development of Dictyostelium discoideum
Author(s) -
OHMORI TAKASHI,
MAEDA YASUO
Publication year - 1986
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1986.00169.x
Subject(s) - dictyostelium discoideum , chemotaxis , cell sorting , group cohesiveness , microbiology and biotechnology , biology , sorting , slug , slime mold , cell , receptor , ecology , genetics , gene , psychology , social psychology , computer science , programming language
Cell sorting behavior was observed during the development of Dictyostelium discoideum Ax‐2, between cells grown with [G(+) cells] and without [G(−) cells] glucose. Development of the G(−) cells was about 2‐3 hr faster, as reflected by differences in chemotactic sensitivity of the cells and cell cohesiveness. Among various mixing combinations of G(−) and G(+) cells, the most clear sorting occured when vegetative G(+) cells were mixed with G(−) cells which had been allowed to develop for 3 hr, the G(−) cells being located in the anterior prestalk region of a migrating slug. In contrast, vegetative G(−) cells moved to the posterior prespore region of a slug when mixed with G(+) cells which had developed for 6 hr. These findings indicate a close relationship of the cellular developmental stage to the sorting behavior. Possible implications of the differential chemotactic ability and cohesiveness for the sorting mechanism are disscussed.