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Rôle du Système Nerveux Sur la Prolifération Cellulaire des Blastèmes de Régénération de Membre de Triton ( Pleurodeles Waltlii Michah)
Author(s) -
BOILLY BÉI,
OUDKHIR MUSTAPHA,
LASSALLE BERNARD
Publication year - 1985
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1985.00129.x
Subject(s) - denervation , mesenchymal stem cell , microbiology and biotechnology , biology , chemistry , anatomy
Cellular proliferation of both epidermal and mesenchymal cells of denerved cone stage limb blastemas ( Pleurodeles waltlii Michah) was studied in vivo. The mitotic index and thymidine 3 H incorporation (autoradiography following short term (1 hr) incubation and scintigraphy) show that denervation causes a significant decrease in the cellular proliferation (about 70% 4 days after denervation). Denervation affects first the mesenchymal cells, the proliferation of epidermal cells declines later. These results are discussed in term of cellular cycle.