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Persistence of Disorganized Pathways and Tortuous Trajectories of Regenerating Retinal Fibers in the Adult Newt Cynops pyrrhogaster
Author(s) -
FUJISAWA HAJIME
Publication year - 1981
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1981.00215.x
Subject(s) - tectum , retinal , optic tract , anatomy , biology , optic tectum , metamorphosis , optic nerve , neuroscience , persistence (discontinuity) , retina , visual system , regeneration (biology) , microbiology and biotechnology , central nervous system , larva , midbrain , ecology , geology , geotechnical engineering , biochemistry
The anatomical pathways and trajectories of regenerating retinal fibers within the optic tract and tectum of adult newts were examined, 7 months after transection of the optic nerve. In spite of restoration of retinotopic ordered central connection within the tectum, the pathways of individual regenerating retinal fibers within the optic tract were greatly disorganized; the misrouted retinal fibers exhibited tortuous trajectories on the tectal surface in approach to their sites of normal innervation. These results suggest that the regenerating retinal fibers with abnormal pathways and tortuous trajectories can be maintained provided they are in contact with appropriate targets.