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INSTABILITY OF MESSENGER AND RIBOSOMAL RNA IN A GLUE‐PROTEIN MUTANT OF Bombyx mori
Author(s) -
KAMIJO SEIJI,
KAWAGUCHI YUTAKA,
FUJII HIROSHI,
SAKAGUCHI BUNGO,
DOIRA HIROSHI,
KUHARA SATORU,
ASO YOICHI,
KOGA KATSUMI,
HAYASHI KATSUYA,
SHIMOTOHNO KUNITADA
Publication year - 1978
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1978.00283.x
Subject(s) - bombyx mori , rna , messenger rna , mutant , glue , microbiology and biotechnology , biology , ribosomal rna , gene , biochemistry , materials science , composite material
The mucous glands of Bombyx pupae secrete glue proteins which attach deposited eggs to the mounting sheet. A mutant of a dominant gene, named no glue (Ng) , produces nonadhesive eggs which have a low capacity for glue‐protein synthesis. In the present study it was shown that the mucous glands of Ng silkworms showed rapid degradation of mRNA as well as rRNA during development; this may cause the low capacity for glue‐protein synthesis in the mutant organ. In contrast, the mucous glands of normal silkworms showed a significant increase in content of RNA's until the maximum rate of glue‐protein synthesis was achieved. The degradation of RNA in the Ng mucous gland was inhibited by actinomycin D injected into the body fluid. Thus it is supposed that the Ng gene codes for a presumptive controller RNA, which would be the mediator of RNA instability in the mucous glands of Ng pupae.