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CYCLIC NUCLEOTIDE‐DEPENDENT PROTEIN KINASES FROM SILKWORM EGGS: OCCURRENCE OF TWO CYCLIC NUCLEOTIDE‐DEPENDENT PROTEIN KINASES, CHANGES IN THEIR ACTIVITIES AND LEVELS OF CYCLIC NUCLEOTIDES DURING DEVELOPMENT OF THE EGGS
Author(s) -
TAKAHASHI SUSUMU Y.,
OHOKA TADAKAZU,
HANAOKA KAZUNORI,
KAGEYAMA TAKASHI,
OHNISHI EIJI
Publication year - 1975
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1975.00227.x
Subject(s) - cyclic nucleotide , kinase , protein kinase a , nucleotide , biology , ask1 , biochemistry , c raf , microbiology and biotechnology , mitogen activated protein kinase kinase , gene
Two cyclic nucleotide‐dependent protein kinases, designated as protein kinase‐I and ‐II, were obtained from the eggs of the silkworm, Bombyx mori . Protein kinase‐I is highly dependent on cGMP, whereas protein kinase‐II is dependent on cAMP. In developing non‐diapause eggs, the level of cyclic nucleotide‐dependent protein kinase activity is quite high but that in the diapause eggs is not. The developmental changes in the two protein kinases and the level of cyclic nucleotides were also studied during the development of the eggs.