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AN ANALYSIS ON THE TROPISM IN HVJ (SENDAI VIRUS) INFECTION: MANIFESTATION OF HIGH VIRAL SUSCEPTIBILITY IN SPREADING CULTURES OF ISOLATED ALLANTOIC EPITHELIAL CELLS OF THE CHICK EMBRYO
Author(s) -
WATANABE KAZUO,
OKADA YOSHIO
Publication year - 1975
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1975.00061.x
Subject(s) - sendai virus , chorioallantoic membrane , biology , tropism , embryo , in vitro , virology , virus , epithelium , cell culture , microbiology and biotechnology , genetics
By culturing pure allantoic epithelial cells separated from the chorioallantoic membrane of a 10‐day‐old chick embryo, sheets of monolayered epithelial cells were obtained and maintained for at least one week. These cells were highly susceptible to infection with HVJ (Sendai virus) in vitro . In similarly cultured mesenchymal cells of the chorioallantoic membrane, the susceptibility was found to be very low. It was concluded that the tropism observed in HVJ infection in vitro can be explained by differences in the susceptibility to HVJ among various cell types.