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DNA CONTENTS IN PURKINJE CELLS AND INNER GRANULE NEURONS IN THE DEVELOPING RAT CEREBELLUM
Author(s) -
FUJITA SETSUYA,
HATTORI TAKANORI,
FUKUDA MASARU,
KITAMURA TADAHISA
Publication year - 1974
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1974.00205.x
Subject(s) - cerebellum , feulgen stain , dna , neuroblast , biology , granule (geology) , microbiology and biotechnology , dna synthesis , ploidy , neuroscience , biochemistry , neurogenesis , gene , paleontology
Cytophotometric studies revealed that the content of Feulgen DNA in Purkinje cells in the developing rat cerebellum remains at the diploid level throughout the postnatal life. No evidence was found to suggest resumption of DNA synthesis in the neurons. This finding is in accord with autoradiographic observations that neuroblasts once differentiated from matrix cells do not synthesize DNA nor divide again.