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INTERACTIONS OF 1‐METHYLADENINE AND THE SURFACE OF STARFISH OOCYTE
Author(s) -
SHORTRIDGE KATHRYN,
LOSEK BARBARA,
LEE HAROLD H.
Publication year - 1974
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1974.00075.x
Subject(s) - starfish , oocyte , chemistry , microbiology and biotechnology , biology , ecology , embryo
Three metabolic inhibitors, mycostatin, concanavalin A (Con A) and cytochalasin B (CB) were used to study the interactions between l‐methyladenine (1‐MA) and the starfish oocyte surface leading to germinal vesicle breakdown (GVB). Mycostatin and Con A had no obvious effects on GVB. CB did not inhibit, but did delay GVB. This delaying effect was interpreted as having multiple 1‐MA reactive “sites” on the surface. The results also suggested that not all of them were needed to react with 1‐MA to bring about GVB.