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THE SYNTHESIS OF COLLAGEN DURING THE DEVELOPMENT OF ANAL‐FIN PROCESSES IN ETHISTERONE *‐TREATED FEMALES OF ORYZIAS LATIPES
Author(s) -
UWA HIROSHI
Publication year - 1971
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1111/j.1440-169x.1971.00119.x
Subject(s) - hydroxyproline , proline , chemistry , oryzias , amino acid , medicine , biochemistry , endocrinology , biology , gene
The synthesis of collagen during the development of anal‐fin processes induced by ethisterone was studied by the autoradiographies of tritiated proline (Pro‐T) and hydroxyproline (HyPro‐T). The rapid incorporation of Pro‐T was initiated in the screloblast masses between 48 and 72 hr of ethisterone treatment. The increased incorporation of HyPro‐T was also detected in the screloblast masses after 48 hr. Furthermore, the grains of both radioactive amino acids were distributed distinctly in the horny substance secreted by the screloblast masses at and after 72 hr. It is suggested that the rapid increase in incorporation of labelled amino acids is mainly due to the collagen synthesis, and that the synthesis of collagen is initiated in the screloblast masses between 48 and 72 hr of the treatment.