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DO WE NEED MOLECULAR TOMOGRAPHY OF A CELL AND HOW CAN IT BE ACHIEVED?
Author(s) -
Chen YiZhang,
Chen XiaoPing
Publication year - 2008
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.2008.04926.x
Subject(s) - intracellular , molecular imaging , tomography , cell , biophysics , computational biology , chemistry , biological system , computer science , nanotechnology , biology , materials science , biochemistry , physics , microbiology and biotechnology , optics , in vivo
SUMMARY1 The spatial relationship between intracellular molecules and their local concentrations are two critical parameters required for a better understanding of protein–protein interactions in the cell. 2 Determination of the local concentration of proteins in individual cells using more sophisticated techniques and determination of the spatial relationship between a molecular platform and its partners is essential for allow us to obtain more convincing and concrete scientific conclusions. 3 As a reasonable goal, development of molecular tomography of the cell is proposed.