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EFFECT OF DRIED‐BONITO BROTH ON PERIPHERAL BLOOD FLOW IN HUMANS: RELATIONSHIP TO IMPROVEMENT OF MOOD STATES
Author(s) -
Nozawa Yoshizu,
Kuroda Motonaka,
Noguchi Takanori
Publication year - 2007
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.2007.04789.x
Subject(s) - mood , ingestion , bonito , placebo , blood flow , peripheral , medicine , profile of mood states , peripheral blood , endocrinology , cardiology , physiology , psychiatry , biology , pathology , alternative medicine , fishery , fish <actinopterygii>
SUMMARY1 Dried‐bonito broth (DBB) has been shown to have various physiological effects to reduce fatigue in both animals and humans. 2 To evaluate whether DBB can improve peripheral blood circulation and improve mood states, a double‐blind, placebo‐controlled, cross‐over study was performed in healthy female subjects. 3 As a result of 2 weeks’ intervention with DBB, subjects showed improved mood states and increased peripheral blood flow. 4 Changes in blood flow during DBB ingestion were significantly correlated with total mood disturbance ( r = – 0.38, P < 0.05): blood flow increased in subjects whose mental states were markedly improved. No significant correlations were found for placebo ingestion. The results suggest that DBB might improve mental condition by increasing blood flow; that is, by enhancing peripheral circulation.