SPECIES VARIABILITY IN CARDIOVASCULAR RESEARCH: THE EXAMPLE OF ADRENOCORTICOTROPHIN‐INDUCED HYPERTENSION | Zendy

Whitworth Judith A | Zendy; Zhang Yi | Zendy; Mangos George | Zendy; Kelly John J | Zendy

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SPECIES VARIABILITY IN CARDIOVASCULAR RESEARCH: THE EXAMPLE OF ADRENOCORTICOTROPHIN‐INDUCED HYPERTENSION

Author(s) -

Whitworth Judith A,

Zhang Yi,

Mangos George,

Kelly John J

Publication year - 2006

Publication title -

clinical and experimental pharmacology and physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.752

H-Index - 103

eISSN - 1440-1681

pISSN - 0305-1870

DOI - 10.1111/j.1440-1681.2006.04460.x

Subject(s) - animal study , animal studies , human studies , medicine , animal model , endocrinology , physiology , biology , surgery

SUMMARY1 Lawrie Beilin has contributed greatly to international hypertension research through both animal and human studies. 2 Animals are used in biomedical research to gain insights that can be extrapolated ultimately to humans. 3 A simple experimental manipulation, adrenocorticotrophin (ACTH) administration, has a range of different cardiovascular effects in different species. 4 Caution should be exercised in extrapolating data from animals to humans.

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