Premium
EMBRYONIC GLOBINS OF THE MARSUPIAL THE TAMMAR WALLABY (MACROPUS EUGENII): BIRD LIKE AND MAMMAL LIKE
Author(s) -
Holland Robert AB,
Gooley Andrew A.,
Hope Rory M.
Publication year - 1998
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.1998.tb02288.x
Subject(s) - globin , biology , tammar wallaby , marsupial , embryonic stem cell , macropus , embryogenesis , monophyly , hemoglobin , phylogenetic tree , evolutionary biology , embryo , microbiology and biotechnology , genetics , zoology , gene , biochemistry , clade
SUMMARY 1. Tammar Wallaby embryonic blood has been shown to have three α‐like and two β‐like globin chains in its four haemoglobin components and partial sequences of several chains have been determined. 2. The major embryonic β‐like chain (ɛ) is similar to other mammalian embryonic p‐like chains on the basis of sequencing its first 60 amino acids. 3. There is another embryonic β‐like chain present in one haemoglobin component. It was designated to and, in its first 54 amino acids, it has features that are more like avian globins than mammalian globins. 4. The one α‐like embryonic globin sequenced has mammalian rather than avian characteristics. 5. A provisional phylogenetic tree of β‐like globins has been determined. The Tammar ω‐globin forms a monophyletic group with marsupial and other mammalian embryonic globins; the to‐globin forms a monophyletic group with bird adult and embryonic globins.