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AXONAL PROJECTIONS FROM RESPIRATORY CENTRES TOWARDS THE ROSTRAL VENTROLATERAL MEDULLA IN THE RAT
Author(s) -
Pilowsky Paul,
Wakefield Bruce,
Minson Jane,
LlewellynSmith Ida,
Chalmers John
Publication year - 1992
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.1992.tb00466.x
Subject(s) - rostral ventrolateral medulla , brainstem , efferent , medulla , medulla oblongata , tyrosine hydroxylase , respiratory system , retrograde tracing , neuroscience , anterograde tracing , biology , axoplasmic transport , anatomy , electrophysiology , central nervous system , afferent , dopamine
SUMMARY 1. Efferent pathways from brainstem respiratory centres towards bulbospinal tyrosine hydroxylase immunoreactive neurons were identified in the rat using a combination of electrophysiology, retrograde and anterograde tract‐tracing, and immunohistoehemistry. 2. Varicose axons originating from respiratory centres were found in close apposition to bulbospinal tyrosine hydroxylase immunoreactive neurons in the ventrolateral medulla. 3. These findings support the idea that respiratory rhythms in sympathetic nerves may be due to a synaptic connection between brainstem respiratory neurons and bulbospinal tyrosine hydroxylase immunoreactive neurons of the CI cell group.