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HYPOTHESIS: ISCHAEMIC PLAQUE NECROSIS AS THE INITIATOR OF UNSTABLE ANGINA/ACUTE MYOCARDIAL INFARCTION?
Author(s) -
Boyd G. W.
Publication year - 1990
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.1990.tb01309.x
Subject(s) - medicine , cardiology , vasa vasorum , myocardial infarction , unstable angina , artery , infarction , angina , necrosis , coronary arteries , blood supply , surgery
SUMMARY 1. Coronary atherosclerotic plaque complications are important in precipitating acute coronary events such as unstable angina and myocardial infarction. 2. The hypothesis is put forward that plaque complications are initiated by increases in local coronary artery tone sufficient to cut off the vasa vasorum blood supply to the plaque and result in its ischaemic necrosis.