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INCREASED VASODILATOR RESPONSE DURING STIMULATION OF CARDIOPULMONARY BARORECEPTORS IN BORDERLINE HYPERTENSIVES
Author(s) -
Girerd X.,
Chanudet X.,
Larroque P.,
Clement R.,
London G.,
Safar M.
Publication year - 1989
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.1989.tb03006.x
Subject(s) - supine position , medicine , forearm , baroreceptor , vasodilation , mean arterial pressure , heart rate , basal (medicine) , blood pressure , cardiology , anesthesia , stimulation , surgery , insulin
SUMMARY1 The effects of passive leg elevation on the forearm circulation were compared in 14 borderline hypertensive and 16 normotensive men. 2 In the supine position, mean arterial pressure (MAP), heart rate (HR) and forearm blood flow (FBF) were significantly greater in borderline hypertensives. 3 With leg raising, MAP and HR did not change significantly from basal values. FBF increased by +0.6 ± 0.2 (s.e.m.) mL/min/100 mL P<0.02) in normotensives and by + 1.3 ± 0.2 mL/min/100 mL P<0.001) in hypertensives (P for difference between groups <0.05).