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HISTAMINE AND CARBACHOL CONTRACTILE RESPONSES IN PROXIMAL AND DISTAL AIRWAYS OF THE RABBIT
Author(s) -
Armour C. L.,
Black J. L.,
Berend N.
Publication year - 1985
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.1985.tb00298.x
Subject(s) - carbachol , histamine , airway , parenchyma , medicine , lung , anatomy , small airways , pathology , chemistry , anesthesia , stimulation
SUMMARY 1. Airway preparations from the trachea, main bronchi, subsegmental bronchi and the parenchyma of rabbits were studied. 2. The proximal airways, the trachea and main bronchi, were less sensitive to histamine than the distal airways of the subsegmental bronchi and lung parenchymal strip. 3. The proximal airways were more sensitive to carbachol than the distal airways. 4. These results may assist in the interpretation of airway responses in vivo.