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CAPTOPRIL IN MILD AND SEVERE HYPERTENSION
Author(s) -
Walter N. M. A.,
Whitworth Judith A.,
KincaidSmith Priscilla
Publication year - 1980
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.1980.tb00095.x
Subject(s) - captopril , medicine , cardiology , blood pressure
SUMMARY 1. Ten patients with mild essential hypertension and nine with severe treatment‐resistant hypertension were treated with captopril. 2. Supine blood pressure was controlled in 9/10 patients with mild hypertension (four with addition of propranolol). 3. There was no correlation between blood pressure fall and initial plasma renin concentration in patients with mild hypertension. 4. Captopril (plus diuretic and/or propranolol) controlled only 4/9 patients with severe hypertension. 5. Four patients developed reversible dysgeusia and one a skin rash.