PROCEEDINGS OF THE AUSTRALIAN SOCIETY FOR MEDICAL RESEARCH

SESSION 1 1. Recombinant DNA: Significance for medical research . J. Shine 2. New perspectives on immunoglobulin genes revealed by recombinant DNA technology. Suzanne Cory SESSION 2 3. Pyrimidine metabolism in rodent malaria . Julie Bennett, Annette Gero and W.J. O'Sullivan 4. Phosphoglycerate kinase deficiency . L.G. Svirklys, C.S. Lee and W.J. O'Sullivan 5. Radioimmunometric assay of high molecular weight factor VIII (FVIII) . Lena Hau, J. Koutts, Jean Perkin and Margaret A. Howard 6. Cyclic nucleotides and chemiluminescence in macrophages. N.H. Hunt, R.L. Smith and M.J. Weidemann 7. An evaluation of the functional capacity of human monocytes . N.J. DeYoung and P.G. Gill 8. Differential patterns of cultured erythroid progenitor behaviour in congenital and acquired erythroblast disorders. F.C. Firkin and S. Russell 9. Are lupus lymphocytotoxins anti‐i agglutinins? C. Witt and R.L. Dawkins 10. Detection of blood group like antigens on t lymphocytes from patients with acute leukaemia . S. Pullen and P. Hersey SESSION 3 11. The central control of fasting gastro‐intestinal activity . D.M. Ingram and B.N. Catch‐pole 12. Colchicine increases intrinsic factor receptors in pregnant mouse intestinal epithelium. S . Shamir, N.D. Gallagher and J. A. Robertson, A. W. Morrow 13. Mechanism of mucus secretion in rat and mouse gastric mucosa . N.D. Yeomans and S.J. Millar 14. Cholelithiasis–abnormal regulation of cholesterol 7α‐hydroxylase? C.T. Kwok, W. Burnett and I.R. Hardie 15. Defective intestinal glucose transport in viral enteritis . R.W. Shepherd, J. Telch, D. Butler, M. Perdue, J.R. Hamilton and D.G. Gall 16. The significance of non transferrin bound iron in haemochromatosis . R.G. Batey, A.W. Morrow 17. The role of the liver in the regulation of serum ferritin . U. Mack, J.W. Halliday, R.A. Ferris, W.G.E. Cooksley and L.W. Powell 18. Role of the liver in cobalamin storage during cyanocobalamin and hydroxycobalamin loading . J.A. Owens and W.G.E. Cooksley SESSION 4 19. Baroreceptor denervation and brain catecholamines in the rat . J.P. Chalmers, M.A. Petty and J.L. Reid 20. A simple mathematical model of overdrive suppression of the sinoatrial node in man . A. Helfgott, W.F. Heddle and A.M. Tonkin 21. Analysis of post‐pacing sinus cycle length sequences in man . W.F. Heddle, A. Helfgott and A.M. Tonkin 22. Age dependence of myocardial Na + ‐K + ‐ATPase activity . A.J. Marsh, B.L. Lloyd and R.R. Taylor 23. Collagen synthesis during hypertrophy of the right ventricle of the dog heart . M.P. Sparrow, Caroline M. Bonnin, and R.R. Taylor 24. Myocardial protein degradation after aortic stenosis . J.H. Steer and B.E. Hopkins 25. Temperature dependence of muscle function in malignant hyperthermic swine . J.S. Sullivan and M.A. Denborough 26. Smoke and pulmonary emphysema . W.F. Green and A.J. Woolcock SESSION 5 27. Inhibitors of natural killer cell activity released by tumour cells. J.J . Zaunders, J.A. Werkmeister and P. Hersey 28. Monitoring tumour growth in patients with melanoma . P. Hersey, E. Murray, P. Ruell and W.H. McCarthy 29. Antibody from breast cancer patient sera to human breast carcinoma cell lines detected by antibody dependent cellular cytotoxicity . M.J. Plain, R.H. Whitehead, and D.G. Jose 30. Monoclonal antibodies against differentiation antigens of human lymphocytes–preparation and analysis . H. Zola, I.G.R. Beckman, J. Bradley, D.A. Brooks, P.J. McNamara & Miriam E. Thomas 31. Human lymphocyte antigens studied by flow microfluorimetry with hybridoma antibodies . D.A. Brooks B. Milthorpe. I. Taylor and H. Zola 32. Rufus–A tool in computer analysis of case studies . D.M. Bennett SESSION 6 33. Effect of EDTA and PGE 1 on liberation of β‐thromboglobulin from stored platelets . L.J. Tunbridge, S.E. Watts, E.M. Lesnikowski, R.J. Kimber and J.V. Lloyd 34. Assessment of the recovery of platelet cyclooxygenase from aspirin effect using a radioimmunoassay for thromboxane B 2 . M. Greaves, R. Roche and P.A. Castaldi 35. Inhibition of human platelet function by the polyunsaturated fat, eicosapentaenoic acid–implications for the prevention of vascular disease . N.G. Ardlie and J.A. Jakubowski 36. Inhibition of prostacyclin (PGI 2 ) generation in rat mesenteric vasculature . R.D. Nolan, G.J. Dusting and T.J. Martin 37. Arachidonic acid metabolism in central and peripheral airways in vitro . H.W. Mitchell and M.A. Denborough 38. Effect of indomethacin on antidiuretic hormone stimulated water permeability . Cheryl Ray SESSION 7 39. The effect of pancreatic juice and bile salts on cholesterol esterification during in vivo absorption in rats . Shirley, M. Watt 40. Soybean saponins and bile salt binding: in vitro and in vivo observations . G.D. Calvert, R.A. Yeates and L.F. Blight 41. Induction of xylitol metabolism in the gut flora of the rat . A.M. Rofe, R. Krishnan, R. Bias, R.A.J. Conyers and J.B. Edwards 42. Phosphocitrate, a new compound for consideration in the control of biological calcification . G. Williams, E.S. Holdsworth and J.D. Sallis 43. Serum lipoproteins and apoproteins in familial hypercholesterolaemia (FH) . P. Poulis, I.H. Craig and G. Hill 44. Effects of polyunsaturated (P) and saturated (S) fat feeding on serum lipoproteins and platelet function in man . I. H. Craig, J.V. Lloyd, P.J. Phillips, D. Watts and A. Bracken SECTION 8 45. Evidence for the involvement of viruses in aid . K.T. Holmes, B.R. Hawkins, P.H. Kay, G. Harnett and R.L. Dawkins 46. How does D‐penicillamine influence autoantibody induction? J.A. Carrano, P.J. Zilko, M.J. Garlepp, B.L. McDonald and R.L. Dawkins 47. Factors affecting titres of antibodies to the acetylcholine receptor . M.J. Garlepp, J.W.M. Lawton, F.T. Christiansen, P. Hollingsworth, J. Hendrie, G. Luciani and R.L. Dawkins 48. Innoculation route determines the effect of presensitization on graft survival . G.C. Saueracker, R.L. Dawkins and P. Hurst 49. Inhibition of leukocyte adherence (LAI) using liver associated antigens in patients with acute and chronic liver diseases . I.M. Roberts, J.W. Halliday, W.J. Halliday W.G.E. Cooksley, W. Burnett, J.F. Kerr and L.W. Powell 50. Selective isolation of allergens. Affinity purification of allergens from the common house dust mites . S. Krilis, B.A. Baldo and A. Basten SESSION 9 51. Suppressor cell activity in a proliferative disorder of T cells . Ann Kupa, Miriam E. Thomas, Helen Moore, J. Bradley, H. Zola, M. Hooper, P. Harding 52. Effects of converting enzyme inhibition with captopril on urinary kallikrein and kinin excretion . B.H. Clappison, C.I. Johnston and W.P. Anderson 53. Lithium administration and urinary electrolyte excretion in the rat . S. Carney, L. Thompson, M. Ralston and T. Morgan 54. Stimulation of renal Na‐K‐ATPase by ouabain . W.R. Adam and J. Danks 55. NADPH independent metabolism of paracetamol and protein covalent binding in rabbit kidney . J. Mohandas, J.Q. Chensee, Safaa Mohamed, I.C. Calder and G.G. Duggin 56. Formation and handling of the glutathione conjugate of paracetamol . K. Healey, I.C. Calder, S.J. Hart, M.C. Smail, K.R. Emslie and J.D. Tange 57. The liver drug metabolizing complex: kinetic studies using chloramphenicol . D.J. O'Shannessy and P.E.B. Reilly 58. The development of an assay for hepatic antipyrine hydroxylase activity and the effect of smoking on it . E.A. McDonald, W.G.E. Cooksley and L.W. Powell SESSION 10 59. Stimulation of plasma 1,25‐Dihydroxyvitamin D by parathyroid extract (PTE) . J.A. Eisman, J.D. Wark and R.L. Prince 60. Partial purification of the 1,25‐dihydroxyvitamin D receptor protein from chicken duodenum . E. Sher, J. Moseley and J. A. Eisman 61. Histamine H 2 receptor antagonist: radioreceptor assay for antiandrogenic side effects . Paul Pearce and John W. Funder 62. Steroid hormone receptors in human benign prostatic hypertrophy (BPH) W.D. Tilley, D.D. Keightley and V.R. Marshall 63. Radioreceptor assay of plasma free glucocorticoid activity. B.A.K . Khalid, and J.W. Funder 64. Familial elevation of plasma thyroxine binding leading to raised serum T 4 and apparent T4 insensitivity in euthyroid subjects . J.W. Barlow, D.J. Topliss, E.L. White, J.W. Funder and J.R. Stockigt SESSION 11 65. Dissociation between Na‐K ATPase and beta‐adrenergic receptors in hypothyroidism . R. White and G. Jerums 66. Nature of adenosine deaminating activity in adenosine deaminase deficient severe combined immunodeficiency . Martin B. Van der Weyden, Lorraine Bailey, Ian Jack and John Ziegler 67. Radioimmunoassays of serum nucleosides . W.B. Deveski, M.H.N. Tattersail, & N.P.B. Dudman 68. Ecto‐triphosphatase deficiency: enzymatic basis for increased sensivity of leukaemic human lymphocytes to deoxynucleosides . S.K. Piddington, E. Tripp, M.H.N. Tattersall & R.M. Fox 69. Thymidine toxicity in human leukaemic lymphocytes–Mechanism of rescue by deoxy‐cytidine . F. Tripp, M.H.N. Tattersall and R.M. Fox 70. The effects of antiviral lipids in human milk on mouse mammary tumour virus . R.J. Coelen and J.T. May SESSION 12 71. Smoking histories of patients with lung cancer . A.J. Woolcock, L. Cottier, J. Gilbert, T. Saccasin and M. Tattersall 72. Studies of submaxillary gland renin . D.F. Catanzaro, R.T. de Zwart and B.J. Morris 73. Increase in proteolytic activity and renin during selective destruction of protease inhibitors in human plasma . C.H. Lawrence and B.J. Morris 74. Alpha‐adrenergic suppression of renin secretion independent of renal vasoconstriction . Robert Vandongen 75. The effect of intravenous GABA on blood pressure in the rat . G.G. Duggin, C. Baxter, D.J. Horvath, D.J. Tiller, F. Furby 76. Effect of converting enzyme inhibition on ACTH hypertension in sheep . Judith A. Whitworth, J.P. Cochlan, D.A. Denton, D. Fei, B.A. Scoggins and K.W. Stewart SESSION 13 77. Evidence for kinin receptors in smooth muscle: studies using radiolabeled ligand binding . M. Yasujima, C.I. Johnston and P.G. Matthews 78. Enhanced megakaryocyte and platelet recovery in hypertransfused irradiated mice . P.J. Smith, C.W. Jackson, M.A. Whidden and C.C. Edwards 79. Importance of pH effect on platelets . S.E. Watts, L.J. Tunbridge, R.J. Kimber and J.V. Lloyd 80. The requirement for extracellular Ca and Mg ions in platelet aggregation . William Booth 81. Studies on the structure of platelet thromboglobulin . J.R. McGready, T. A. Diggle, C.N. Chesterman and F.J. Morgan 82. Platelet function in myeloproliferative disease . I.L. Smith, T.J. Martin and S. Vaughan 83. The effects of alcohol and dietary protein metabolism in a rat model . L.C. Ward, W.G. Cooksley and S. Chapman SESSION 14 84. Putative peptide transmitters . L.B. Geffen 85. Clinical relevance of amino acid neurotransmitters . D.R. Curtis SESSION 15 86. The funding of medical research in the U.K . J.L. Gowans SESSION 16 87. Vitamin D‐Now . I Maclntyre 88. Calmodulin: an ubiquitous intracellular CA 2+ ‐receptor . Basil D. Roufagalis