Premium
Left atrial type b receptor response during hypothermia in dogs
Author(s) -
Fahim M.
Publication year - 1979
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/j.1440-1681.1979.tb00043.x
Subject(s) - hypothermia , receptor , medicine , q10 , chemistry , endocrinology , anesthesia , anatomy , respiration
Summary 1. The response of left atrial type B receptors to hypothermia and its effect on the V‐wave pressure‐receptor activity relationship was studied in ten anaesthetized and thoracotomized dogs. Hypothermia was produced by surface cooling of the animal. 2. With the drop in the body temperature there was a corresponding fall in the peak frequency of discharge. Reduction in the number of impulses per cardiac cycle and the average resting activity of these receptors became significant only when body temperature fell below 31°C. The Q 10 for these receptors is about 2.5, i.e., similar to that for the other mechanoreceptors and consistent with the view that these receptors are in parallel with the muscle fibres. 3. The V‐wave pressure‐receptor activity relationships were not altered by acute hypothermia.