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Rheumatoid neutrophilic dermatosis with tense blister formation: A case report and review of the literature
Author(s) -
Fujio Yumi,
Funakoshi Takeru,
Nakayama Kaori,
Amagai Masayuki,
Ohyama Manabu
Publication year - 2014
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2012.00963.x
Subject(s) - dapsone , medicine , rheumatoid arthritis , blisters , dermatology , surgery , immunology
We report a 78‐year‐old woman with rheumatoid neutrophilic dermatosis ( RND ) presenting with tense blisters; an extremely rare manifestation of this condition. Systemic corticosteroid was of limited efficacy, while dapsone was effective. A literature review of four similar cases showed that tense blisters in this type of RND tended to appear on the lower extremities of aged, female rheumatoid arthritis patients. Of note, half of the cases were resistant to corticosteroids, as anti‐neutrophil agents are reported to be effective. Accordingly, it is important to recognise this unusual manifestation for the timely initiation of appropriate therapy.