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A possible chemopreventive role for photodynamic therapy in G orlin syndrome: a report of basal cell carcinoma reduction and review of literature
Author(s) -
Wolfe Christopher M.,
Green W. Harris,
Cognetta Armand B.,
Hatfield H. Keith
Publication year - 2013
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2012.00922.x
Subject(s) - medicine , basal cell carcinoma , photodynamic therapy , basal cell nevus syndrome , disfigurement , basal cell , dermatology , treatment modality , vismodegib , modalities , pathology , cancer research , oncology , surgery , chemistry , organic chemistry , social science , sociology
Multiple basal cell carcinomas ( BCC ) are a significant cause of morbidity and disfigurement in patients with naevoid basal cell carcinoma syndrome ( NBCCS ). Chemopreventive strategies are needed to reduce the formation of new BCC in these patients. Appropriate evidence‐based guidelines for photodynamic therapy chemoprevention in NBCCS do not exist. We herein report one patient treated with methyl aminolevulinate PDT with red light (630 nm) activation to continue sustained chemoprevention following other BCC chemopreventive modalities and a relevant literature review.