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Endothelin receptor antagonist bosentan improves the dermal sclerosis in a patient with systemic sclerosis
Author(s) -
Nishibu Akiko,
Sakai Erika,
Oyama Noritaka,
Yamamoto Toshiyuki
Publication year - 2012
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2010.00719.x
Subject(s) - bosentan , medicine , endothelin receptor antagonist , endothelin receptor , antagonist , dermatology , receptor antagonist , multiple sclerosis , receptor , pharmacology , immunology
We report a case of systemic sclerosis with interstitial pneumonia and severe pulmonary hypertension treated with bosentan, an endothelin receptor antagonist. Within a short period of administration of the bosentan the skin sclerosis improved.