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Primary cutaneous carcinosarcoma: Dermoscopic and immunohistochemical features
Author(s) -
Upjohn Edward,
Braue Anna,
Ryan Andrew
Publication year - 2010
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2009.00587.x
Subject(s) - medicine , carcinosarcoma , pathology , immunohistochemistry , histology , nodule (geology) , basal cell carcinoma , biopsy , atypical fibroxanthoma , giant cell , sarcoma , lesion , carcinoma , basal cell , biology , paleontology
A 73‐year‐old man presented a 9‐month history of an enlarging nodule on his right temple. Dermoscopy revealed a non‐pigmented lesion with ulceration, fibrosis and pale globules. An excisional biopsy was carried out and histology showed a biphasic tumour with a basal cell carcinoma like epithelial component and a dermal undifferentiated sarcoma, with pleomorphic spindle cells and numerous osteoclast‐like giant cells. Based on immunohistochemistry findings, a diagnosis of primary cutaneous carcinosarcoma was made and the patient underwent wide local excision.