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Treatment of refractory pyoderma gangrenosum with intravenous immunoglobulin
Author(s) -
De Zwaan Sally E,
Iland Harry J,
Damian Diona L
Publication year - 2009
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2008.00506.x
Subject(s) - medicine , pyoderma gangrenosum , prednisone , refractory (planetary science) , adverse effect , antibody , immunoglobulin a , intravenous immunoglobulins , corticosteroid , dermatology , surgery , pyoderma , diabetes mellitus , immunoglobulin g , gastroenterology , immunology , disease , endocrinology , physics , astrobiology
SUMMARY We report a patient with pyoderma gangrenosum successfully treated with intravenous immunoglobulin. He had previously been treated for 4 years with high‐dose corticosteroids and had developed insulin‐dependent diabetes mellitus. Multiple corticosteroid‐sparing agents had failed or were contraindicated. He developed no adverse effects from intravenous immunoglobulin, which allowed reduction of his prednisone to 3 mg/day, and his ulcer has completely healed.