Premium
Cutaneous penile and perianal Crohn's disease treated with a combination of medical and surgical interventions
Author(s) -
Rajpara Sanjay M,
Siddha Sanjay K,
Ormerod Anthony D,
Kerr Keith M,
Kolhe Prahalad S
Publication year - 2008
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2007.00413.x
Subject(s) - medicine , clobetasol propionate , surgery , penis , crohn's disease , thalidomide , dermatology , methotrexate , disease , minocycline , prednisolone , isotretinoin , skin grafting , corticosteroid , antibiotics , multiple myeloma , microbiology and biotechnology , acne , biology
SUMMARY A 73‐year‐old man presented with fistulizing cutaneous Crohn's disease of the penis and perianal area without involvement of the gastrointestinal tract. The disease failed to respond to topical clobetasol propionate and oral cyclosporin and methotrexate. A combination treatment of minocycline, thalidomide and prednisolone brought the disease under control and induced remission. Surgery with excision and skin grafting were required to produce cure.