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Cutaneous Rosai‐Dorfman disease
Author(s) -
Manifold R.,
Reid C.,
O'Brien V.,
Sidhu S.,
Ibbetson J.
Publication year - 2007
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2007.00408_2.x
Subject(s) - medicine , rosai–dorfman disease , sinus histiocytosis with massive lymphadenopathy , histopathology , cervical lymphadenopathy , pathology , histiocytosis , biopsy , erythrocyte sedimentation rate , sinus (botany) , lymph node , dermatology , disease , surgery , botany , biology , genus
Rosai‐Dorfman disease (RDD), originally designated sinus histiocytosis with massive lymphadenopathy, typically presents in young adults with massive, painless cervical lymphadenopathy, fever, leucocytosis, elevated erythrocyte sedimentation rate (ESR) and hypogammaglobulinaemia. We present a case of cutaneous RDD with no evidence of lymph node involvement. The initial presentation of disease was in the pituitary gland and the nasal sinuses. Clinical examination revealed non‐specific skin coloured nodules involving the back and right side of the face. A skin biopsy, however, showed the typical histological and immunohistochemical features of RDD. Clincial photos and histopathology will be presented with a discussion of RDD, including cutaneous RDD.