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Wolf’s isotopic response: Rosacea appearing at the site of healed herpes zoster
Author(s) -
Sezer Engin,
Koseoglu Resit D,
Filiz Nurper
Publication year - 2006
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2006.00270.x
Subject(s) - medicine , rosacea , dermatology , rash , ectasia , isotretinoin , folliculitis , pathology , acne
SUMMARY A 40‐year‐old man developed an erythematous rash on the right side of his face 3 weeks after a herpes zoster infection at the same location. Examination revealed an erythematous papular eruption and telangiectasias along the ophthalmic and maxillary divisions of the right trigeminal nerve, exactly at the site of the consistent with previous herpes zoster infection, Wolf’s isotopic response. Histological examination showed vascular ectatic dilatation and perivascular and perifollicular infiltration of lymphocytes and histiocytes consistent with rosacea. The rash was resistant to oral doxycycline and topical metronidazole 1% cream and resolved with oral isotretinoin therapy.