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Paraneoplastic pemphigus: A brief update
Author(s) -
Wade Martin S,
Black Martin M
Publication year - 2005
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2005.126_1.x
Subject(s) - paraneoplastic pemphigus , medicine , pemphigus , dermatology , antigen , immunology , autoantibody , antibody
SUMMARY First described in 1990, paraneoplastic pemphigus is an autoimmune condition that causes considerable morbidity, is resistant to therapy and is frequently fatal. Clinical heterogeneity is being recognized as more cases are reported and the documented auto‐antigen profile is also increasing. Target antigens are now known to be not restricted to the skin, suggesting that this condition is part of a paraneoplastic autoimmune multiorgan syndrome.