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Pityriasis rubra pilaris and focal acantholytic dyskeratosis
Author(s) -
Cowen Peter,
O'Keefe Rodney
Publication year - 1997
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1997.tb01099.x
Subject(s) - pityriasis rubra pilaris , medicine , dermatology , dyskeratosis , acantholysis , dyskeratosis congenita , hyperkeratosis , psoriasis , dna , genetics , telomere , biology , antibody , immunology , autoantibody
SUMMARY A 65‐year‐old man presented with a widespread erythematous maculopapular eruption. Skin biopsy showed spongiosis and focal acantholytic dyskeratosis consistent with Grover's disease. Clinically the eruption evolved to erythroderma with typical features of pityriasis rubra pilaris. On review of the histology, changes consistent with this diagnosis were also present in addition to the acantholytic dyskeratosis.