Premium
Regression in skin tumours: A common phenomenon
Author(s) -
Branetson R StC,
Halliday G M
Publication year - 1997
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1997.tb01013.x
Subject(s) - medicine , keratoacanthoma , basal cell epithelioma , basal cell carcinoma , epithelioma , melanoma , pathology , regression , incidence (geometry) , basal (medicine) , carcinoma , basal cell , dermatology , cancer research , psychology , physics , insulin , psychoanalysis , optics
Regression in epithelial skin tumours is a common phenomenon, and this may be partial or complete. In keratoacanthoma and familial self-healing epithelioma, nearly all the tumours regress completely. The incidence of total regression in melanoma and basal cell carcinoma is unknown, but in 25% of melanomas and 50% of basal cell carcinomas there is evidence of partial regression on histological examination. Previous studies carried out in our laboratories have indicated that regression of skin tumours is likely to be mediated by activated CD4+ T lymphocytes, possibly via cytokine secretion.