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Two cases of protothecosis in Nagoya, Japan
Author(s) -
Matsumoto Yoshinari,
Shibata Masayuki,
Adachi Ayumi,
Ohashi Masaru,
Kanbe Toshio,
Tanaka Kenji
Publication year - 1996
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1996.tb01082.x
Subject(s) - ketoconazole , itraconazole , medicine , dermatology , agar , biology , antifungal , bacteria , genetics
SUMMARY Two cases of protothecosis caused by Prototheca wickerhamii have been reported from Nagoya in a 12 year period. In both cases the infection presented on the cheeks of otherwise healthy women. Biopsies showed numerous PAS positive staining organisms with the distinctive mulberry‐like endosporulation in the dermis. Prototheca wickerhamii was identified on sugar assimilation tests of colonies isolated from tissue on Sabouraud agar. Case 1 responded to 11 months of oral ketoconazole therapy. Case 2 might not respond to itraconazole. The source of the infections has not been identified.