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GLUCAGONOMA SYNDROME WITH INCREASED LACTATE DEHYDROGENASE ISOENZYMES: OCTREOTIDE TREATMENT
Author(s) -
Siller Gregory M.,
Strutton Geoffrey M.,
Moore Geoffrey A.,
Kanowski And David M.,
Nedwich Judith A.
Publication year - 1994
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1994.tb01792.x
Subject(s) - glucagonoma , medicine , hyperglucagonemia , glucagon , octreotide , pancreas , endocrinology , diabetes mellitus , lactate dehydrogenase , gastroenterology , pathology , insulin , somatostatin , enzyme , biochemistry , biology
SUMMARY Glucagonoma Syndrome is a rare syndrome comprising hyperglucagonemia, diabetes mellitus, necrolytic migratory erythema and hypoaminoacidemia in the setting of a glucagon producing, alpha cell tumour of the pancreas. We report a case of Glucagonoma Syndrome palliatively treated successfully with octreotide. In addition to classical clinical and biochemical findings, this patient also had a Glomus Jugulars tumour, and Empty Sella Syndrome and demonstrated an unusual pattern of plasma lactate dehydrogenase isoenzymes, features not previously reported in this syndrome.