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CUTANEOUS CRYPTOCOCCOSIS: RECURRENCE FOLLOWING ORAL FLUCONAZOLE TREATMENT
Author(s) -
Cooper Celia M.,
Gordon David L.,
Reid Catherine,
Philpot C. Ross
Publication year - 1992
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1992.tb00088.x
Subject(s) - cryptococcosis , fluconazole , medicine , cryptococcus neoformans , antifungal , dermatology , mycosis , lesion , cryptococcus , surgery , pathology , microbiology and biotechnology , biology
S ummary A case of recurrent cutaneous cryptococcosis in an immunocompromised patient is described. The patient presented with a non‐healing cutaneous ulcer due to infection with Cryptococcus neoformans. Extensive investigation failed to reveal any evidence of associated systemic cryptococcosis. Treatment with oral fluconazole resulted in complete resolution of the ulcer but after several months a second cutaneous cryptococcal lesion appeared, strongly suggesting dissemination from an underlying systemic focus. This case illustrates the hazards associated with making a diagnosis of isolated cutaneous cryptococcosis and the necessity for prolonged follow‐up of patients who present in this way.