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KAWASAKI SYNDROME
Author(s) -
Esterly Nancy B.,
Wortmann Dorothy W.
Publication year - 1990
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1990.tb00653.x
Subject(s) - medicine , kawasaki disease , mucocutaneous lymph node syndrome , etiology , eponym , vasculitis , systemic vasculitis , pediatrics , dermatology , mucocutaneous zone , acute coronary syndrome , disease , pathology , surgery , cardiology , artery , physics , acoustics , myocardial infarction
S ummary Kawasaki syndrome is an acute multisystem inflammatory disease of young children first described by Tomasaku Kawasaki in the Japanese literature in 1967 1 He reported 50 cases of this entity under the rubric of acute febrile mucocutaneous lymph node syndrome, a designation that has more recently been superseded by the eponym Kawasaki syndrome. The disorder was further delineated and brought to the attention of American pediatricians in 1974 2 . Recognition of the syndrome followed rapidly, and Melish, Hicks and Larson published the first series of American cases from Hawaii in 1976 3 . Subsequently, Kawasaki syndrome has been documented worldwide. Although the disorder is known to be a systemic vasculitis with predilection for the coronary arteries, the etiology has remained obscure despite intense investigative efforts.