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EPIDERMODYSPLASIA VERRUCIFORMIS
Author(s) -
DyallSmith Delwyn,
Cowen Peter,
Varigos George
Publication year - 1989
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1989.tb00424.x
Subject(s) - epidermodysplasia verruciformis , medicine , dermatology , basal cell , human papillomavirus , disease , pathology
S ummary A patient with epidermodysplasia verruciformis was followed over a ten year period. This rare genetic disorder, characterised by papillomavirus‐associated skin lesions and squamous cell carcinomas, is difficult to manager and invariably shortens the lifespan due to metastases from skin carcinomas. In our case, we confirmed the diagnosis using nucleic acid hybridisation, at high stringency, to cloned papillomavirus DNA. Relentless progression of disease occurred despite varied and increasingly vigorous treatment modalities.