Premium
TREATMENT OF ALOPECIA AREATA WITH DIPHENCYPRONE
Author(s) -
Hatzis J.,
Georgiotouo K.,
Kostakis P.,
Anastasiadis G.,
Tosca A.,
Varelzidis A.,
Straigos J.
Publication year - 1988
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1988.tb01223.x
Subject(s) - alopecia areata , medicine , vellus hair , dermatology , vitiligo , hair loss , minoxidil , scalp
SUMMARY Forty‐five patients with extensive alopecia areata were treated by local application of diphencyprone. Only eleven had satisfactory regrowth of hair. Six had moderate regrowth, and of the remaining 28 some showed regrowth of vellus hair and others had no response. The side effects of the treatment consisted of intense allergic or irritant reactions, febrile reactions, anaphylactic reaction with fainting, and vitiligo. In twelve patients progressive desensitisation was observed. As the effectiveness of this treatment is low and side effects are common and sometimes severe, we conclude that diphencyprone has no advantage in the treatment of alopecia areata.