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DITHRANOL IN A CREAM BASE IN THE TREATMENT OF PSORIASIS
Author(s) -
Wargon O.,
Paver W. K. A.
Publication year - 1982
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1982.tb00743.x
Subject(s) - dithranol , medicine , dermatology , psoriasis , irritation , immunology
S ummary In this study, twenty patients with mild or moderately severe psoriasis were divided into two groups. In one group the combination of PUVA therapy and dithranol cream was compared with PUVA therapy alone. In the other group dithranol 0.2% in Lassar's paste was compared with dithranol cream. On an overall assessment, patients improved after treatment for a period of four weeks. In the group comparing dithranol cream with 0.2% dithranol in Lassar's paste, seven of the eight patients preferred dithranol cream. Both preparations caused staining of the skin and clothes but irritation of the normal skin was more prevalent in those areas treated with dithranol 0.2% in Lassar's paste. The dithranol cream formulation (Di‐Cream) was shown to be a stable, effective formulation that was more acceptable to patients than dithranol in Lassar's paste.